Expertise: Pediatric endocrine diseases: dwarfism, precocious puberty, delayed puberty, abnormal growth and development and other pediatric endocrine diseases.

BIO: Dr. CAI Depei serves as the multi-site physician at Jiahui Health. He graduated from Beijing Medical College in 1968 and obtained graduate degree in Shanghai Medical University in 1981. He is currently a professor and doctoral supervisor at the Children’s Hospital of Fudan University. He is the Honorary Vice Chairman of the Endocrine Reproductive Physiology Committee of the Chinese Physiological Society, the Executive Director of the Sexual Medicine Committee of the Chinese Society of Traditional Chinese Medicine, a member of the Professional Committee of the Shanghai Society of Integrative Medicine, and a Fellow of the American Academy of World Traditional Medicine.

Medical Expertise: Dr. CAI mainly engaged in the clinical and scientific research of pediatric endocrine diseases and puberty medicine, and expertise at treating children's precocious puberty, delayed puberty, growth abnormality and other pediatric endocrine diseases by using the combination of traditional Chinese and Western medicine.

Overview of scientific research: Since 1994, Dr. CAI has undertaken and completed several research projects on precocious puberty in children for the National Natural Science Foundation of China, the Ministry of Health of China and the State Administration of Traditional Chinese Medicine. Using neurobiology, molecular biology and other modern biomedical experimental methods. It has been proved that the traditional Chinese medicine formula can effectively regulate the hypothalamic-pituitary gonadotropic and growth-promoting functions of children at the level of neuroendocrine regulation and gene expression.
The recently completed National Natural Science Foundation of China (NSFC) research project, ‘Research on the Mechanism of Sexual Development Abnormalities in Children Caused by Environmental Endocrine Disruptors and Their Treatment with Traditional Chinese Medicines’, has monitored the serum levels of many kinds of environmental endocrine disruptors (EEDs) in large samples of normal children and children suffering from precocious puberty, both in the nation and abroad, and have made correlation analyses with the degree of lesions in the reproductive organs of the affected children. Correlation analyses were made with the degree of lesions in the reproductive organs of the children, and it was found that the pollution of EEDs has become more common in normal children, and it was confirmed that the pollution of EEDs has a close relationship with the onset of precocious puberty in children and is one of the important causative factors of the disease. A series of traditional Chinese medicine treatment protocols for the reproductive toxicity of EEDs have been formulated to provide pharmacological interventions for children who have been poisoned by EEDs pollution, and both clinical and animal experiments have confirmed that the traditional Chinese medicine treatment protocols used have obvious antagonistic effects on the reproductive toxicity of EEDs. Modern biomedical experimental methods have been used to elucidate the mechanism of action of the Chinese medicines used. These research results not only provide an innovative and effective treatment programme suitable for the national situation for the general population affected by the pollution and toxicity of EEDs, especially children and adolescents, but also provide a theoretical basis for the development of a series of Chinese medicinal preparations with independent intellectual property rights.

Dr. CAI Depei's consultation fee, including first and follow up visit, starts at ￥1,200.

Dr. YUAN Dandan is currently a pediatrician at Jiahui Medical. Dr. YUAN graduated from the Shanghai Medical College of Fudan University in 2013 with a doctoral degree. After graduation, she worked at Shanghai Children's Hospital for over a decade,and took part in the "Sydney Child Health Program" by Sydney Children’s Hospital. She has been working in the outpatient and inpatient services of the endocrinology department, including teaching residents and fellows. She is also a skillful doctor for common pediatric diseases.
As an investigator (main SUB-I), Dr. Yuan has participated in several GCP programs. She has also contributed to the writing of professional books in the field of pediatrics, such as "Diagnostic and Therapeutic Analysis of Typical Cases in Pediatric Endocrinology", "Precocious Puberty and Delayed Adolescence", and "Diagnosis and Treatment of Precocious Puberty in Children".