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    • Helicobacter pylori (Hp) is the known bacteria living in the human stomach, and the infection rate in China has reached 50-67% (1,2). As the main pathogenic factor of chronic gastritis and peptic ulcer, it is also the Class I pathogenic factor of gastric cancer. Eradication of Hp has a preventive effect on gastric cancer (3,4). Moreover, it can effectively relieve the related symptoms caused by Hp in functional dyspepsia or other stomach diseases, and improve the degree of atrophic gastritis atrophy and intestinal metaplasia.


      The eradication of H.pylori infection is based on the empirical antibiotic treatment strategy. The difficulties in the current eradication of Hp include an increasing resistance rate to many routine antibiotics, which leads to a decreasing success rate of Helicobacter pylori eradication year by year. The eradication rate of Hp in previous first-line triple therapy has decreased from more than 90% in the 1990s to less than 60% at present (3,4).


      As an infectious disease, the best eradication for H.pylori infection is individualized treatment combined with the sensitivity of H. Pylori related antibiotics. Therefore, if the drug resistance information of antibiotics can be obtained before eradication treatment, no matter the initial treatment, initial treatment failure or the failure of eradication twice (refractory H. Pylori infection), doctors tend to recommend targeted drug selection based on drug sensitivity results, especially for refractory HP infection, family history of gastric cancer, or moderate and severe gastric mucosal atrophy, intestinal metaplasia or dysplasia found in gastroscopy. In this way, not only can satisfactory eradication efficacy be achieved, but also can effectively avoid unreasonable use of antibiotics and reduce the generation of antibiotic resistance.


      References:
      [1]中华医学会消化病学分会幽门螺杆菌和消化性溃疡学组,全国幽门螺杆菌研究协作组.第五次全国幽门螺杆菌感染处理共识报告[J].中华消化杂志,2017,037(006):364-378.
      [2]Xie Y,et al. Long-term follow-up of Helicobacter pylori reinfection and its risk factors after initial eradication: a large-scale multicentre, prospective open cohort, observational study. Emerg Microbes Infect, 2020 Dec;9(1).
      [3]Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. Gut 2012; 61:646.
      [4]Chey WD, Leontiadis GI, Howden CW, Moss SF. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol 2017; 112:212.

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    • The Gastroenterology Department of Jiahui Health can provide a variety of routine detection methods for HP infection, including breath test, HP serum antibody, HP fecal antigen, and HP detection in gastric mucosa, etc. Moreover, we cooperates with the laboratory department of Jiahui to carry out drug sensitivity and resistance detection projects of Helicobacter pylori. In addition to routine first-line and second-line HP eradication treatment, we can also guide the plan of HP eradication based on the drug sensitivity detection results. Effectively improve the eradication rate of refractory Hp, to achieve the ideal individual therapeutic effect.

    • Languages

      Location

      Doctors

      XIA Lu, MD, PhD

      Department:
      Gastroenterology
      Liver Clinic
      Inflammatory Bowel Disease Clinic
      Gastro-intestinal Polyp Clinic
      GI GERD Clinic
      Pancreas Clinic
      Pelvic Floor Dysfunction Clinic
      H. Pylori Clinic
      Location:
      Jiahui International Hospital (Shanghai)
      Jiahui Health (Jing'an)
      Jiahui Health (Yangpu)
      Languages:
      普通话,  English
      Doctor's bio

      Dr. Lu XIA

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      William CAO, MD, PhD

      Department:
      Gastroenterology
      Liver Clinic
      Inflammatory Bowel Disease Clinic
      Gastro-intestinal Polyp Clinic
      GI GERD Clinic
      Pancreas Clinic
      Biliopancreatic endoscopy clinic
      H. Pylori Clinic
      Location:
      Jiahui International Hospital (Shanghai)
      Jiahui Health (Jing'an)
      Jiahui Health (Yangpu)
      Languages:
      普通话,  English
      Doctor's bio

      Dr. William CAO is a gastroenterologist at Jiahui Health. Dr. Cao obtained his bachelor's degree in Clinical Medic...

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      Michael SUN, MD

      Department:
      Gastroenterology
      Gastro-intestinal Polyp Clinic
      Anorectal disease clinic
      Biliopancreatic endoscopy clinic
      H. Pylori Clinic
      Location:
      Jiahui International Hospital (Shanghai)
      Languages:
      普通话,  English
      Doctor's bio

      Dr. Michael SUN is now a gastroenterologist at Jiahui Health.

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      HUANG Qin, MD

      Department:
      Gastroenterology
      Gastro-intestinal Polyp Clinic
      Anorectal disease clinic
      Constipation Clinic
      H. Pylori Clinic
      Location:
      Jiahui International Hospital (Shanghai)
      Jiahui Health (Jing'an)
      Jiahui Health (Yangpu)
      Languages:
      普通话,  English
      Doctor's bio

      Dr. HUANG Qin, practice as a gastroenterologist at Jiahui Health. Dr. Huang received his medical degree from Ganna...

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      Jane SONG, MD

      Department:
      Gastroenterology
      Gastro-intestinal Polyp Clinic
      Anorectal disease clinic
      Constipation Clinic
      H. Pylori Clinic
      Location:
      Jiahui International Hospital (Shanghai)
      Jiahui Health (Yangpu)
      Languages:
      普通话,  English
      Doctor's bio

      Dr. Jing Song (Jane Song) is gastroenterologist in Jiahui international hospital. She graduated from Fudan Univers...

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    • Affordable prices set your mind at ease

      Service Name Price Unit Price
      Primary care consultation fee per visit 300-1000
      Specialist consultation fee per visit 500-1500
      * Consultation fee is determined by clinicians according to the complexity of the patient’s condition. Jiahui Health reserves the right to interpret and adjust prices. All prices in RMB.

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    2021-06-01
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